And on Wednesday morning, Warren released a new radio spot that -- without mentioning Brown -- focused on the national GOP agenda as harmful to woman. "This can't be happening in 2012, right? But it's not just one extreme candidate in Missouri; it's part of a Republican pattern," says the ad's narrator after playing audio of Akin's remarks. "Just imagine if Republicans win the White House, or gain control of the U.S. Senate." Among other things, the commercial goes on to cite equal pay again, Paul Ryan cosponsoring legislation "that could outlaw birth control pills" and Mitt Romney wanting to "get rid of Planned Parenthood." The narrator notes that if the GOP control gains control of the Senate, they "decide who sits on the Supreme Court and whether we could lose Roe v. Wade." The radio ad may also be a sign of the direction where Warren's campaign is heading as fall approaches: Brown remains popular even as Mitt Romney and the national Republican Party are unpopular in the state, and shifting to a message of "A vote for Scott Brown means a vote for a GOP-controlled Senate" would make sense. So far, neither candidate has run an explicitly negative television ad attacking the other -- and with outside groups staying out of the race due to an agreement between Brown and Warren, no one else is attacking either candidate yet over the airwaves.